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There are 8 thirteen-letter words beginning with SIGN

SIGNALISATIONsignalisation n. Alternative spelling of signalization.
SIGNALISATION n. the process of signalising.
SIGNALIZATIONsignalization n. The process of signalizing; characterization or differentiation.
SIGNALIZATION n. the act of signalizing.
SIGNIFICANCESsignificances n. Plural of significance.
SIGNIFICANCE n. something that is conveyed as a meaning often obscurely or indirectly.
SIGNIFICANTLYsignificantly adv. In a significant manner or to a significant extent.
SIGNIFICANT adv. having meaning.
SIGNIFICATIONsignification n. The act of signifying, or something that is signified; significance.
signification n. Evidence for the existence of something.
signification n. A meaning of a word.
SIGNIFICATIVEsignificative adj. (Usually followed by of) That tends to signify or indicate; indicative.
significative adj. That has meaning or significance; significant.
SIGNIFICATIVE adj. significant, suggestive.
SIGNIFICATORSsignificators n. Plural of significator.
SIGNIFICATOR n. in astrology, a planet ruling a house.
SIGNIFICATORYsignificatory adj. Significant; having signification.
SIGNIFICATORY adj. of or relating to a significator, in astrology, a planet ruling a house.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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