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There are 4 words beginning with RUBEFAC

RUBEFACIENTrubefacient adj. Making red.
rubefacient n. (Medicine) A substance for topical application that produces redness of the skin, e.g. by dilating the capillaries.
RUBEFACIENT n. an agent that is a gentle irritant producing increased blood circulation and reddening of the skin where it is applied.
RUBEFACTIONrubefaction n. The act or process of making red.
RUBEFACTION n. reddening.
RUBEFACIENTSrubefacients n. Plural of rubefacient.
RUBEFACIENT n. an agent that is a gentle irritant producing increased blood circulation and reddening of the skin where it is applied.
RUBEFACTIONSrubefactions n. Plural of rubefaction.
RUBEFACTION n. reddening.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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