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There are 2 eleven-letter words beginning with RUBEF

RUBEFACIENTrubefacient adj. Making red.
rubefacient n. (Medicine) A substance for topical application that produces redness of the skin, e.g. by dilating the capillaries.
RUBEFACIENT n. an agent that is a gentle irritant producing increased blood circulation and reddening of the skin where it is applied.
RUBEFACTIONrubefaction n. The act or process of making red.
RUBEFACTION n. reddening.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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