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There is only one twelve-letter word beginning with PREDETER

PREDETERMINEpredetermine v. (Transitive) To determine or decide in advance.
predetermine v. (Transitive) To doom by previous decree; to foredoom.
pre-determine v. Alternative form of predetermine.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org.

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