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There are 2 twelve-letter words beginning with PREDESI

PREDESIGNATE	• predesignate adj. Designated in advance. • predesignate adj. (Logic, of a proposition) Having its quantity indicated by a verbal sign, as with "all", "none", etc. • predesignate v. To designate in advance.
PREDESIGNING	• predesigning v. Present participle of predesign. • PREDESIGN v. to design in advance.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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English Wiktionary: 2 words
Scrabble in French: no word
Scrabble in Spanish: no word
Scrabble in Italian: no word
Scrabble in German: no word
Scrabble in Romanian: no word

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