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There is only one twelve-letter word beginning with PLEXIME

PLEXIMETRIESPLEXIMETRY n. the use of a pleximeter, a small, hard, elastic plate, as of ivory, bone, or rubber, placed in contact with body to receive the blow, in examination by mediate percussion.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definition is a short excerpt from the 1Word.ws.

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