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There are 2 twelve-letter words beginning with PROSCR

PROSCRIPTIONproscription n. A prohibition.
proscription n. (History) Decree of condemnation toward one or more persons, especially in the Roman antiquity.
proscription n. The act of proscribing, or its result.
PROSCRIPTIVEproscriptive adj. Proscribing or prohibiting, for example as according to a norm or standard.
PROSCRIPTIVE adj. relating to proscription.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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