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There are 2 seven-letter words beginning with PROFA

PROFACEproface interj. (Obsolete) A familiar salutation or welcome offered by a host before a meal or drinks are served.
PROFACE interj. (Shakespeare) may it profit you, a phrase of welcome.
PROFANEprofane adj. Unclean; ritually impure; unholy, desecrating a holy place or thing.
profane adj. Not sacred or holy, unconsecrated; relating to non-religious matters, secular.
profane adj. Treating sacred things with contempt, disrespect, irreverence, or scorn; blasphemous, impious.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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