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There is only one twelve-letter word beginning with PITYR

PITYROSPORUMPityrosporum prop.n. Former name of Malassezia (“fungus genus”).
PITYROSPORUM n. a yeastlike fungus which can cause pityriasis.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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