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There are 4 eight-letter words beginning with PRUR

PRURIENTprurient adj. Uneasy with desire; itching; especially, having a lascivious anxiety or propensity; lustful.
prurient adj. Arousing or appealing to sexual desire.
prurient adj. Curious, especially inappropriately so.
PRURIGOSprurigos n. Plural of prurigo.
PRURIGO n. (Latin) a chronic skin condition characterized by itching and the presence of small pale pimples.
PRURITICpruritic adj. (Medicine) Intensely itchy.
PRURITIC adj. of or like pruritus, itching of the skin.
PRURITUSpruritus n. (Medicine) severe itching, especially of undamaged skin; caused by allergy, infection, lymphoma etc.
PRURITUS n. (Latin) intense itching.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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