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There are 3 twelve-letter words beginning with PEST

PESTILENTIALpestilential adj. Of or relating to pestilence or plague.
pestilential adj. (Figurative) Having a harmful moral effect (especially one that is believed to spread in the manner of pestilence).
pestilential adj. (Figurative) Causing irritation or annoyance.
PESTOLOGICALpestological adj. Relating to pestology.
PESTOLOGICAL adj. related to pestology, the science of pests.
PESTOLOGISTSpestologists n. Plural of pestologist.
PESTOLOGIST n. one who studies pestology.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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