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There are 5 five-letter words beginning with PIO

PIONSpions n. Plural of pion.
PION n. an elementary particle of the meson family.
PIONYpiony n. Obsolete form of peony.
PIONY n. (obsolete) a peony, also PAEONY, PINEY, PINY, PIONEY.
PIOUSpious adj. Of or pertaining to piety, exhibiting piety, devout, godfearing.
pious adj. Relating to religion or religious works.
pious adj. Insisting on or making a show of one’s own virtue, especially in comparison to others; sanctimonious…
PIOYEPIOYE n. (Scots) a homemade firework, also PEEOY, PIOY.
PIOYSPIOY n. (Scots) a homemade firework, also PEEOY, PIOYE.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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