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There are 4 eight-letter words beginning with OSTI

OSTINATIostinati n. Plural of ostinato.
OSTINATO n. (Italian) a constantly recurring melodic fragment.
OSTINATOostinato n. (Music) A piece of melody, a chord progression, or a bass figure that is repeated over and over as a…
OSTINATO n. (Italian) a constantly recurring melodic fragment.
OSTIOLARostiolar adj. Of or pertaining to the ostiole.
OSTIOLAR adj. relating to an ostiole, a small opening.
OSTIOLESostioles n. Plural of ostiole.
OSTIOLE n. a small bodily opening.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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