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There are 2 six-letter words beginning with OSTI

OSTIALostial adj. (Anatomy) Relating to any orifice, or ostium.
OSTIAL adj. relating to an ostium, the mouth of a river or a mouthlike opening.
OSTIUMostium n. A small opening or orifice, as in a body organ or passage.
ostium n. Any of the small openings or pores in a sponge.
ostium n. The mouth of a river.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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