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There are 2 six-letter words beginning with OPER

OPERASoperas n. Plural of opera.
OPERA n. a form of musical drama.
OPERONoperon n. A unit of genetic material that functions in a coordinated manner by means of an operator, a promoter…
OPERON n. a group of genes operating as a unit.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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