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There are 3 eight-letter words beginning with OPO

OPOPANAXopopanax n. (Obsolete) A gum resin obtained from the root of Opopanax chironium, formerly used in medicine.
opopanax n. A perfume made from the gum resin of various trees.
opopanax n. The popinac or opopanax tree (Acacia farnesiana, syn. Vachellia farnesiana), an acacia of America.
OPORICESOPORICE n. (Greek) an old medicine made from summer fruits.
OPOSSUMSopossums n. Plural of opossum.
OPOSSUM n. (Native American) any of various small or medium-sized marsupial mammals, mostly arboreal.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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