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There are 5 seven-letter words beginning with OPI

OPIATEDopiated v. Simple past tense and past participle of opiate.
opiated adj. Treated with an opiate.
opiated adj. Under the influence of an opiate.
OPIATESopiates n. Plural of opiate.
opiates v. Third-person singular simple present indicative form of opiate.
OPIATE v. to treat with opium.
OPININGopining v. Present participle of opine.
opining n. The act of giving one’s opinion.
OPINE v. to hold as an opinion.
OPINIONopinion n. A belief, judgment or perspective that a person has formed, either through objective or subjective reasoning…
opinion n. The judgment or sentiment which the mind forms of persons or things; estimation.
opinion n. (Obsolete) Favorable estimation; hence, consideration; reputation; fame; public sentiment or esteem.
OPIOIDSopioids n. Plural of opioid.
OPIOID n. a peptide that acts like opium.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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