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There are 8 seven-letter words beginning with OPE

OPENERSopeners n. Plural of opener.
OPENER n. one that opens.
OPENESTopenest v. (Archaic) second-person singular simple present form of open.
OPEN adj. affording unobstructed access, passage, or view.
OPENINGopening v. Present participle of open.
opening adj. Pertaining to the start or beginning of a series of events.
opening adj. (Cricket) describing the first period of play, usually up to the fall of the first wicket; describing…
OPERANDoperand n. (Mathematics, computing) A quantity to which an operator is applied (in 3−𝑥, the operands of the subtraction…
OPERAND n. a quantity on which a mathematical or logical operation is (to be) performed.
OPERANToperant adj. That operates to produce an effect.
operant n. An operative person or thing.
operant n. (Psychology) Any of a class of behaviors that produce consequences by operating (i.e., acting) upon the environment.
OPERATEoperate v. (Transitive or intransitive) To perform a work or labour; to exert power or strength, physical or mechanical; to act.
operate v. (Transitive or intransitive) To produce an appropriate physical effect; to issue in the result designed…
operate v. (Transitive or intransitive) To act or produce effect on the mind; to exert moral power or influence.
OPERONSoperons n. Plural of operon.
OPERON n. a group of genes operating as a unit.
OPEROSEoperose adj. (Now rare) Of a person: busy, industrious, or painstaking.
operose adj. (Now rare) Made with or requiring a lot of labour; painstaking, laborious.
operose adj. (Now rare) Tedious, wearisome.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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