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There is only one four-letter word beginning with OSE

OSESoses n. (Colloquial) The various sugars ending in -ose, such as sucrose, lactose, glucose, and fructose.
OSes n. Plural of OS.
-oses suff. Plural of -osis.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org.

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