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There are 6 twelve-letter words beginning with OPE

OPEIDOSCOPESopeidoscopes n. Plural of opeidoscope.
OPEIDOSCOPE n. an instrument for illustrating sound by means of light.
OPENHANDEDLYopenhandedly adv. Alternative form of open-handedly.
open-handedly adv. In an open-handed manner.
OPENHANDED adv. generous.
OPERATICALLYoperatically adv. In an operatic manner.
OPERATIC adv. relating to opera.
OPERATIONISMoperationism n. (Philosophy) The doctrine that the meaning of a term consists of the operation(s) performed in defining it.
OPERATIONISM n. the theory that defines scientific concepts by means of the operations used to prove or determine them, also OPERATIONALISM.
OPERATIONISToperationist n. A proponent of operationism.
OPERATIONIST n. an adherent of operationism.
OPERATORLESSoperatorless adj. Without an operator (person who operates); fully automatic.
OPERATORLESS adj. without an operator.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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