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There are 9 four-letter words beginning with OP

OPAHopah n. Any of various large, colourful, deep-bodied pelagic fish of the family Lamprididae.
OPAH n. a large sea-fish with laterally flattened body, aka sunfish, kingfish.
OPALopal n. (Mineralogy) A mineral consisting, like quartz, of silica, but inferior to quartz in hardness and specific…
opal n. (Biology, genetics, biochemistry) A colloquial name used in molecular biology referring to a particular…
opal n. Any of various lycaenid butterflies of the genus Nesolycaena.
OPASOPA n. (German) a grandfather, also OUPA.
OPEDoped v. Simple past tense and past participle of ope.
op-ed n. A newspaper page containing signed articles by commentators expressing viewpoints that may not agree…
op-ed adj. Of or being a newspaper page, usually opposite the editorial page, that features signed articles expressing…
OPENopen adj. (Usually not comparable) Not closed.
open adj. Not physically drawn together, closed, folded or contracted; extended.
open adj. (Not comparable) Actively conducting or prepared to conduct business.
OPESopes v. Third-person singular simple present indicative form of ope.
OPE v. to open.
OPPOoppo n. (Countable, UK, slang) A friend, associate or colleague.
oppo n. (Uncountable, US, politics, informal) Research into one’s opponent’s family, friends, and past, which…
OPPO n. an opposite number or an opponent.
OPTSopts v. Third-person singular simple present indicative form of opt.
OPT v. to decide or choose.
OPUSopus n. (Music) A work of music or set of works with a specified rank in an ordering of a composer’s complete…
opus n. A work, especially of art.
OPUS n. (Latin) a work, esp. an artistic or literary work.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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