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There are 3 eight-letter words beginning with NICOTI

NICOTIANnicotian adj. (Dated) Relating to, or derived from, tobacco.
NICOTIAN n. a tobacco smoker.
NICOTINEnicotine n. (Organic chemistry) An alkaloid (C10H14N2), commonly occurring in the tobacco plant. In small doses…
nicotine n. (Figuratively) Tobacco, cigarettes.
NICOTINE n. a poisonous alkaloid in tobacco, also NICOTIN.
NICOTINSnicotins n. Plural of nicotin.
NICOTIN n. a poisonous alkaloid in tobacco, also NICOTINE.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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