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There are 10 ten-letter words beginning with MELAN

MELANAEMIAmelanaemia n. (Medicine) A morbid condition in which the blood contains black pigment, either floating freely or embedded…
MELANAEMIA n. the presence of melanin in the blood.
MELANCHOLYmelancholy n. (Historical) Black bile, formerly thought to be one of the four "cardinal humours" of animal bodies.
melancholy n. Great sadness or depression, especially of a thoughtful or introspective nature.
melancholy adj. (Literary) Affected with great sadness or depression.
MELANISINGmelanising v. Present participle of melanise.
MELANISE v. to make dark, also MELANIZE.
MELANISTICmelanistic adj. Of, pertaining to, or exhibiting melanism.
MELANISTIC adj. affected with melanism.
MELANIZINGmelanizing v. Present participle of melanize.
melanizing adj. That causes melanization.
MELANIZE v. to make dark, also MELANISE.
MELANOCYTEmelanocyte n. (Medicine, biochemistry, cytology) A cell in the skin that produces the pigment melanin.
MELANOCYTE n. an epidermal cell that can produce melanism.
MELANOMATAmelanomata n. Plural of melanoma.
MELANOMA n. a darkly pigmented tumor.
MELANOSITYmelanosity n. The condition of being melanous; darkness of complexion.
MELANOSITY n. the state of being melanous, swarthy.
MELANOSOMEmelanosome n. (Biology) Any organelle that contains melanin.
MELANOSOME n. a melanin-producing granule in a melanocyte.
MELANURIASmelanurias n. Plural of melanuria.
MELANURIA n. the presence of a dark pigment in the urine.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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