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There are 6 five-letter words beginning with LOS

LOSEDlosed v. (Obsolete) simple past tense and past participle of lose.
losed v. (Obsolete) simple past tense and past participle of loose.
LOSED v. (Spenser) loosed.
LOSELlosel n. (Archaic) A worthless or despicable person, scoundrel.
losel adj. Worthless; wasteful.
LOSEL n. a good for nothing fellow; a vagabond, also LOREL, LORRELL, LOZELL.
LOSENLOSEN v. (Spenser) to loosen.
LOSERloser n. A person who loses; one who fails to win or thrive.
loser n. Something of poor quality.
loser n. A person who is frequently unsuccessful in life.
LOSESloses v. Third-person singular simple present indicative form of lose.
LOSE v. to misplace or be deprived of.
LOSSYlossy adj. (Telecommunications) Of a communication channel, subject to loss of signal strength.
lossy adj. (Power systems) Of an electricity transmission line, subject to various forms of power loss.
lossy adj. (Computing, of an algorithm for converting or compressing data) Reducing the amount of information in data.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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