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There are 9 five-letter words beginning with LOC

LOCALlocal adj. From or in a nearby location.
local adj. (Computing, of a resource) Connected directly to a particular computer, processor, etc.; able to be accessed offline.
local adj. (Computing, of a variable or identifier) Having limited scope (either lexical or dynamic); only being…
LOCHEloche n. Alternative form of loach (“kind of fish”).
LOCHE n. a fish of the cod family.
LOCHSlochs n. Plural of loch.
Lochs prop.n. Plural of Loch.
LOCH n. (Scots) a lake.
LOCIELOCIE n. an engine used in logging, also LOCI.
LOCISLOCI n. an engine used in logging, also LOCIE.
LOCKSlocks n. Plural of lock.
locks n. A head of hair; tresses.
locks n. (Colloquial) Dreadlocks.
LOCOSlocos n. Plural of loco.
locos v. Third-person singular simple present indicative form of loco.
LOCO v. to poison with locoweed.
LOCUMlocum n. (Britain, Australia, informal) Short for locum tenens.
locum n. (Britain, Australia, informal) A period working as a locum tenens.
locum n. (Historical) A share in a Genoese trading vessel.
LOCUSlocus n. A place or locality, especially a centre of activity or the scene of a crime.
locus n. (Mathematics) The set of all points whose coordinates satisfy a given equation or condition.
locus n. (Genetics) A fixed position on a chromosome that may be occupied by one or more genes.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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