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There are 5 four-letter words beginning with LOC

LOCAloca n. Plural of locum.
LOCA n. (Nuclear industry) loss-of-coolant accident.
LOCA n. Initialism of Liquid optically clear adhesive.
LOCHloch n. (Ireland, Scotland) A lake.
loch n. (Ireland, Scotland) A bay or arm of the sea.
loch n. Alternative form of lohoch (“medicine taken by licking”).
LOCIloci n. Plural of locus.
LOCI n. an engine used in logging, also LOCIE.
LOCKlock n. Something used for fastening, which can only be opened with a key or combination.
lock n. (Computing, by extension) A mutex or other token restricting access to a resource.
lock n. A segment of a canal or other waterway enclosed by gates, used for raising and lowering boats between levels.
LOCOloco adv. (Music) A direction in written or printed music to be returning to the proper pitch after having played…
loco adj. (Colloquial) Crazy.
loco adj. (Southwestern US) Intoxicated by eating locoweed.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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