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There is only one eight-letter word beginning with GANGREN

GANGRENEgangrene n. The necrosis or rotting of flesh, usually caused by lack of blood supply.
gangrene n. (Figuratively) A damaging or corrupting influence.
gangrene v. (Transitive) To produce gangrene in.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org.

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