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There are 2 six-letter words beginning with GUIN

GUINEAguinea n. (US, slang, derogatory, ethnic slur) A person of Italian descent.
guinea n. (Britain, historical) A gold coin originally worth twenty shillings; later (from 1717 until the adoption…
guinea n. Synonym of guinea fowl.
GUINEPguinep n. Alternative form of genip.
guinep n. Alternative form of quenepa.
GUINEP n. (Tupi) a tropical American tree; its orange-like fruit, also GENIP, GENIPAP, GENIPAPO.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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