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There are 2 four-letter words beginning with GUA

GUANguan n. Any (member) of several species of birds in the genera Aburria, Chamaepetes, Oreophasis, Penelope, Penelopina…
Guan prop.n. A surname.
guan- pref. (Pharmacology) Used to form names of guanidine derivatives used as antihypertensives.
GUARguar n. An annual legume (Cyamopsis tetragonoloba), used as a food for cattle and humans.
Guar. n. (Law) Abbreviation of guaranty.
GUAR n. (Hindi) a legume grown for forage and its seeds which yield guar gum.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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