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There is only one eight-letter word beginning with FRENE

FRENETICfrenetic adj. Fast, harried; having extreme enthusiasm or energy.
frenetic adj. (Obsolete) Mentally deranged, insane.
frenetic adj. (Obsolete, medicine) Characterised by manifestations of delirium or madness.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org.

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