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There is only one eight-letter word beginning with EPIDEM

EPIDEMICepidemic n. A widespread disease that affects many individuals in a population.
epidemic n. (Epidemiology) An occurrence of a disease or disorder in a population at a frequency higher than that…
epidemic n. (Figurative) The spreading of an idea or belief amongst a population.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org.

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