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There are 5 eight-letter words beginning with EPID

EPIDEMICepidemic n. A widespread disease that affects many individuals in a population.
epidemic n. (Epidemiology) An occurrence of a disease or disorder in a population at a frequency higher than that…
epidemic n. (Figurative) The spreading of an idea or belief amongst a population.
EPIDERMSepiderms n. Plural of epiderm.
EPIDERM n. the outermost layer of the skin, also EPIDERMIS.
EPIDOTESepidotes n. Plural of epidote.
EPIDOTE n. a mineral, a silicate of alumina, lime, and oxide of iron, or manganese.
EPIDOTICepidotic adj. Related to, resembling, or containing epidote.
EPIDOTIC adj. resembling or containing epidote.
EPIDURALepidural adj. (Anatomy, relational) Situated on or outside the dura mater.
epidural adj. (Medicine, relational) Of or pertaining to the space immediately outside the dura mater.
epidural n. (Medicine) An injection of anaesthetic into the epidural space of the spine, especially associated with…

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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