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There are 5 five-letter words beginning with DEF

DEFAT	• defat v. To remove fat from a material, especially by the use of solvents. • DEFAT v. to remove fat from.
DEFER	• defer v. (Transitive) To delay or postpone. • defer v. (American football) After winning the opening coin toss, to postpone until the start of the second half… • defer v. (Intransitive) To delay, to wait.
DEFFO	• deffo adj. (Colloquial, Australia, UK, Ireland, Canada, usually with "for") Definite. • deffo adv. (Colloquial, Australia, UK, Ireland, Canada) Definitely. • DEFFO interj. (colloquial) definitely, also DEFO.
DEFIS	• DEFI n. (French) a challenge.
DEFOG	• defog v. (Transitive) To remove the moisture or fog from. • defog v. (Transitive, informal) To make intelligible; to free from confusion. • DEFOG v. to remove fog from e.g. spectacles.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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English Wiktionary: 14 words
Scrabble in French: 5 words
Scrabble in Spanish: no word
Scrabble in Italian: no word
Scrabble in German: no word
Scrabble in Romanian: 2 words

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