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There are 6 six-letter words beginning with ACU

ACUATEacuate adj. Sharpened; sharp-pointed.
acuate v. (Obsolete, transitive) To sharpen; to make pungent; to quicken.
ACUATE v. to sharpen.
ACUITYacuity n. Sharpness or acuteness, as of a needle, wit, etc.
acuity n. The ability to think, see, or hear clearly.
ACUITY n. sharpness.
ACULEIaculei n. Plural of aculeus.
ACULEUS n. (Latin) a prickle growing on the bark, as in some brambles and roses.
ACUMENacumen n. Quickness of perception or discernment; penetration of mind; the faculty of nice discrimination.
acumen n. (Botany) A sharp, tapering point extending from a plant.
acumen n. (Anatomy) A bony, often sharp, protuberance, especially that of the ischium.
ACUTERacuter adj. Comparative form of acute: more acute.
ACUTE adj. sharply pointed.
ACUTESacutes n. Plural of acute.
acutes v. Third-person singular simple present indicative form of acute.
ACUTE n. a type of accent mark.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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