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There is only one five-letter word beginning with AO

AORTAaorta n. (Anatomy) The great artery which carries the blood from the heart to all parts of the body except the…
aorta n. (Figuratively) The liveliest part of something.
AORTA n. (Greek) the main blood vessel from the heart.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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