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There are 16 words containing 2P, 2S, T and 2U

SUPPURATESsuppurates v. Third-person singular simple present indicative form of suppurate.
SUPPURATE v. to discharge pus.
SUPPORTURESSUPPORTURE n. support.
PRESUMPTUOUSpresumptuous adj. Going beyond what is right, proper, or appropriate because of an excess of self-confidence or arrogance.
PRESUMPTUOUS adj. overstepping due bounds (as of propriety or courtesy).
PURPRESTURESpurprestures n. Plural of purpresture.
PURPRESTURE n. encroachment on public property.
SUPPOSITIOUSsuppositious adj. Spurious; substituted for the genuine, counterfeit; fake; supposititious.
suppositious adj. Imaginary; fictitious, pretended to exist.
suppositious adj. Hypothetical, based on supposition; suppositional.
SUPPURATIONSsuppurations n. Plural of suppuration.
SUPPURATION n. the discharge of pus.
SUPPURATIVESsuppuratives n. Plural of suppurative.
SUPPURATIVE n. a suppurative agent.
MULTIPURPOSESSorry, definition not available.
LIPOSCULPTURESLIPOSCULPTURE n. cosmetic surgery on the lips.
PRESUMPTUOUSLYpresumptuously adv. In a presumptuous manner; arrogantly.
PRESUMPTUOUS adv. overstepping due bounds (as of propriety or courtesy).
SUBPOPULATIONSsubpopulations n. Plural of subpopulation.
SUBPOPULATION n. an identifiable fraction or subdivision of a population.
SUPERCOMPUTERSsupercomputers n. Plural of supercomputer.
SUPERCOMPUTER n. a large very fast mainframe used esp. for scientific computations.
SUPPOSITIOUSLYsuppositiously adv. In a suppositious manner.
SUPPOSITIOUS adv. fraudulently substituted, also SUPPOSITITIOUS.
SUPPOSITITIOUSsupposititious adj. (Obsolete) Spurious; substituted for the genuine, counterfeit; fake.
supposititious adj. (Obsolete) Imaginary; fictitious, pretended to exist.
supposititious adj. Supposed or hypothetical.
UNPRESUMPTUOUSunpresumptuous adj. Not presumptuous; modest.
UNPRESUMPTUOUS adj. not presumptuous.
SUPERCOMPUTINGSSUPERCOMPUTING n. computing using a supercomputer, a large very fast mainframe used esp. for scientific computations.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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