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There are 16 words containing 2P, 2S, T and 2U

LIPOSCULPTURESLIPOSCULPTURE n. cosmetic surgery on the lips.
MULTIPURPOSESSorry, definition not available.
PRESUMPTUOUSpresumptuous adj. Going beyond what is right, proper, or appropriate because of an excess of self-confidence or arrogance.
PRESUMPTUOUS adj. overstepping due bounds (as of propriety or courtesy).
PRESUMPTUOUSLYpresumptuously adv. In a presumptuous manner; arrogantly.
PRESUMPTUOUS adv. overstepping due bounds (as of propriety or courtesy).
PURPRESTURESpurprestures n. Plural of purpresture.
PURPRESTURE n. encroachment on public property.
SUBPOPULATIONSsubpopulations n. Plural of subpopulation.
SUBPOPULATION n. an identifiable fraction or subdivision of a population.
SUPERCOMPUTERSsupercomputers n. Plural of supercomputer.
SUPERCOMPUTER n. a large very fast mainframe used esp. for scientific computations.
SUPERCOMPUTINGSSUPERCOMPUTING n. computing using a supercomputer, a large very fast mainframe used esp. for scientific computations.
SUPPORTURESSUPPORTURE n. support.
SUPPOSITIOUSsuppositious adj. Spurious; substituted for the genuine, counterfeit; fake; supposititious.
suppositious adj. Imaginary; fictitious, pretended to exist.
suppositious adj. Hypothetical, based on supposition; suppositional.
SUPPOSITIOUSLYsuppositiously adv. In a suppositious manner.
SUPPOSITIOUS adv. fraudulently substituted, also SUPPOSITITIOUS.
SUPPOSITITIOUSsupposititious adj. (Obsolete) Spurious; substituted for the genuine, counterfeit; fake.
supposititious adj. (Obsolete) Imaginary; fictitious, pretended to exist.
supposititious adj. Supposed or hypothetical.
SUPPURATESsuppurates v. Third-person singular simple present indicative form of suppurate.
SUPPURATE v. to discharge pus.
SUPPURATIONSsuppurations n. Plural of suppuration.
SUPPURATION n. the discharge of pus.
SUPPURATIVESsuppuratives n. Plural of suppurative.
SUPPURATIVE n. a suppurative agent.
UNPRESUMPTUOUSunpresumptuous adj. Not presumptuous; modest.
UNPRESUMPTUOUS adj. not presumptuous.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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