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There are 6 six-letter words containing P, R, S and 2U

PRUNUSprunus n. (Ceramics) A type of traditional decoration on porcelain that depicts the leaves and branches of the…
Prunus prop.n. A taxonomic genus within the family Rosaceae – plums, cherries, peaches, apricots and almonds.
PRUNUS n. (Latin) a genus of tree including plum.
PURSUEpursue v. (Transitive, intransitive) To follow urgently, originally with intent to capture or harm; to chase.
pursue v. (Transitive) To follow, travel down (A particular way, course of action etc.).
pursue v. (Transitive) To aim for, go after (A specified objective, situation etc.).
RUMPUSrumpus n. A noisy, sometimes violent disturbance; noise and confusion; a quarrel.
rumpus n. (New Zealand, Australia, Canada) A rumpus room.
RUMPUS n. a noisy disturbance.
UPRUNSupruns v. Third-person singular simple present indicative form of uprun.
UPRUN v. to run up.
UPRUSHuprush n. An upwards rush.
uprush v. (Intransitive) To rush upward.
UPRUSH v. to rush up.
USURPSusurps v. Third-person singular simple present indicative form of usurp.
USURP v. to seize and hold without legal authority.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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