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There are 12 twelve-letter words containing 2P, T and 2U

MULTIPURPOSEmultipurpose adj. Designed or intended to fit more than one type of function or application; having multiple uses.
multi-purpose adj. Alternative form of multipurpose.
MULTIPURPOSE adj. having many purposes.
OUTPOPULATEDoutpopulated v. Simple past tense and past participle of outpopulate.
OUTPOPULATE v. to surpass in population.
OUTPOPULATESoutpopulates v. Third-person singular simple present indicative form of outpopulate.
OUTPOPULATE v. to surpass in population.
PRESUMPTUOUSpresumptuous adj. Going beyond what is right, proper, or appropriate because of an excess of self-confidence or arrogance.
PRESUMPTUOUS adj. overstepping due bounds (as of propriety or courtesy).
PURPRESTURESpurprestures n. Plural of purpresture.
PURPRESTURE n. encroachment on public property.
SUPPOSITIOUSsuppositious adj. Spurious; substituted for the genuine, counterfeit; fake; supposititious.
suppositious adj. Imaginary; fictitious, pretended to exist.
suppositious adj. Hypothetical, based on supposition; suppositional.
SUPPURATIONSsuppurations n. Plural of suppuration.
SUPPURATION n. the discharge of pus.
SUPPURATIVESsuppuratives n. Plural of suppurative.
SUPPURATIVE n. a suppurative agent.
UNPOPULARITYunpopularity n. The property or degree of being unpopular.
UNPOPULARITY n. the state of being unpopular.
UNPROPITIOUSunpropitious adj. Not propitious; unfavourable, untimely.
UNPROPITIOUS adj. not propitious.
UNSUPPORTIVEunsupportive adj. Not supportive.
UPPERCUTTINGuppercutting v. Present participle of uppercut.
UPPERCUT v. to strike an upward blow.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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