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There are 18 four-letter words containing P, S and Y

ESPYespy v. (Transitive).
espy v. (Intransitive, archaic) To observe as a spy, to spy; also, to examine or observe carefully; or to look out or watch.
espy n. (Countable).
GYPSgyps n. Plural of gyp.
Gyps prop.n. A taxonomic genus within the family Accipitridae – some Old World vultures.
GYP n. pain or discomfort.
HYPShyps n. Plural of hyp.
HYPS prop.n. Initialism of Harvard/Yale/Princeton/Stanford.
hyps- pref. Height.
PAYSpays v. Third-person singular simple present indicative form of pay.
pays n. Plural of pay.
Pays prop.n. Plural of Pay.
POSYposy n. A flower; a small bouquet; a nosegay.
posy n. (Archaic) A verse of poetry, especially a motto or an inscription on a ring.
POSY adj. given to posing, also POSEY.
PRYSPrys prop.n. Plural of Pry.
PRYS v. (obsolete) to price.
PUYSpuys n. Plural of puy.
PUY n. a small volcanic cone.
PYASpyas n. Plural of pya.
PYA n. a copper coin of Burma.
PYESpyes n. Plural of pye.
Pyes prop.n. Plural of Pye.
PYE v. to mix printing type indiscrimately, also PI, PIE.
SPAYspay v. (Transitive) To remove or destroy the ovaries and/or uterus (of a female animal) so that she cannot become pregnant.
spay n. The act of spaying an animal.
spay n. Rare spelling of spayard.
SPRYspry adj. Having great power of leaping or running; nimble; active.
spry adj. Vigorous; lively; cheerful.
Spry prop.n. A surname.
SYPESYPE v. (dialect) to soak through, seep, also SIPE.
SYPHsyph n. (Slang) Syphilis.
SYPH n. a venereal disease, also SYPHILIS.
UPSYupsy interj. Diminutive of upsadaisy.
UPSY n. (obsolete) a carousal, also UPSEE, UPSEY.
YAPSyaps n. Plural of yap.
yaps v. Third-person singular simple present indicative form of yap.
YAP v. to bark shrilly.
YEPSyeps n. (Informal) plural of yep.
Yeps prop.n. Plural of Yep.
YEP n. (colloquial) yes, also YUP.
YIPSyips n. (Informal) A nervous condition which prevents a sportsperson from playing properly; especially a condition…
yips n. Plural of yip.
yips v. Third-person singular simple present indicative form of yip.
YUPSyups n. Plural of yup.
yups part. (Informal) Yes.
YUPs n. Plural of YUP.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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See this list for:

  • English Wiktionary: 58 words
  • Scrabble in French: 3 words
  • Scrabble in Spanish: no word
  • Scrabble in Italian: no word
  • Scrabble in German: 2 words
  • Scrabble in Romanian: no word


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