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There are 20 words containing O, 2P, R, 2S and 2U

PERSPICUOUSperspicuous adj. Clearly expressed, easy to understand; lucid.
perspicuous adj. (Logic) Of a language or notation, such as that of formal propositional calculus: where the process…
perspicuous adj. (Rare) Transparent; translucent.
SUPERGROUPSsupergroups n. Plural of supergroup.
SUPERGROUP n. a pop group made up of established solo artists.
SUPPORTURESSUPPORTURE n. support.
PRESUMPTUOUSpresumptuous adj. Going beyond what is right, proper, or appropriate because of an excess of self-confidence or arrogance.
PRESUMPTUOUS adj. overstepping due bounds (as of propriety or courtesy).
SUPPURATIONSsuppurations n. Plural of suppuration.
SUPPURATION n. the discharge of pus.
UNPROSPEROUSunprosperous adj. Not prosperous.
UNPROSPEROUS adj. not prosperous.
MULTIPURPOSESSorry, definition not available.
PERSPICUOUSLYperspicuously adv. With clarity and lucidity.
PERSPICUOUS adv. easily understood; clearly expressed.
PSEUDOCARPOUSPSEUDOCARPOUS adj. of or like a pseudocarp.
HYPOSULPHUROUShyposulphurous adj. Alternative form of hyposulfurous.
HYPOSULPHUROUS adj. of or derived from hyposulphurous acid.
IMMUNOSUPPRESSimmunosuppress v. (Transitive) To cause immunosuppression in.
IMMUNOSUPPRESS v. to inhibit the body's immune response.
LIPOSCULPTURESLIPOSCULPTURE n. cosmetic surgery on the lips.
PRESUMPTUOUSLYpresumptuously adv. In a presumptuous manner; arrogantly.
PRESUMPTUOUS adv. overstepping due bounds (as of propriety or courtesy).
PSEUDOMORPHOUSpseudomorphous adj. Not having the true form.
PSEUDOMORPHOUS adj. of or like a pseudomorph, also PSEUDOMORPHIC.
PURPOSEFULNESSpurposefulness n. The state of being purposeful.
PURPOSEFUL n. showing purpose.
SUPERCOMPUTERSsupercomputers n. Plural of supercomputer.
SUPERCOMPUTER n. a large very fast mainframe used esp. for scientific computations.
UNPRESUMPTUOUSunpresumptuous adj. Not presumptuous; modest.
UNPRESUMPTUOUS adj. not presumptuous.
UNPROSPEROUSLYunprosperously adv. In an unprosperous manner.
UNPROSPEROUS adv. not prosperous.
PERSPICUOUSNESSperspicuousness n. The state or characteristic of being perspicuous; perspicuity.
PERSPICUOUSNESS n. the state of being perspicuous.
SUPERCOMPUTINGSSUPERCOMPUTING n. computing using a supercomputer, a large very fast mainframe used esp. for scientific computations.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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See this list for:

  • English Wiktionary: 226 words
  • Scrabble in French: 25 words
  • Scrabble in Spanish: 33 words
  • Scrabble in Italian: 4 words
  • Scrabble in German: no word
  • Scrabble in Romanian: 28 words


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