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There are 18 words containing 3O, P, S and X

EXOSPOROUSexosporous adj. Relating to an exospore.
EXOSPOROUS adj. of or like an exospore, the extreme outer wall of a spore; the epispore.
GOOGOLPLEXESgoogolplexes n. Plural of googolplex.
GOOGOLPLEX n. the figure 1 followed by a googol of zeroes (10 raised to the googol power).
ORTHOPYROXENESorthopyroxenes n. Plural of orthopyroxene.
ORTHOPYROXENE n. a member of the pyroxene group of minerals having an orthorhombic crystal structure, such as enstatite and hypersthene.
PARADOXOLOGIESparadoxologies n. Plural of paradoxology.
PARADOXOLOGY n. the holding or maintaining of paradoxes.
PHOTOOXIDATIONSphotooxidations n. Plural of photooxidation.
PHOTOOXIDATION n. oxidation under the influence of radiant energy, as light.
PHOTOOXIDISEPHOTOOXIDISE v. to undergo photooxidation, also PHOTOOXIDIZE.
PHOTOOXIDISEDPHOTOOXIDISE v. to undergo photooxidation, also PHOTOOXIDIZE.
PHOTOOXIDISESPHOTOOXIDISE v. to undergo photooxidation, also PHOTOOXIDIZE.
PHOTOOXIDISINGPHOTOOXIDISE v. to undergo photooxidation, also PHOTOOXIDIZE.
PHOTOOXIDIZESphotooxidizes v. Third-person singular simple present indicative form of photooxidize.
PHOTOOXIDIZE v. to undergo photooxidation, also PHOTOOXIDISE.
PHOTOTOXICITIESphototoxicities n. Plural of phototoxicity.
PHOTOTOXICITY n. the state of being phototoxic.
POORBOXESpoorboxes n. Plural of poorbox.
poor␣boxes n. Plural of poor box.
POORBOX n. a box, esp. one in a church, used for the collection of alms or money for the poor.
PROPAROXYTONESproparoxytones n. Plural of proparoxytone.
PROPAROXYTONE n. in ancient Greek, a word having the acute accent on the third last syllable.
TOXICOPHAGOUSTOXICOPHAGOUS adj. eating poison, also TOXIPHAGOUS.
TOXICOPHOBIASTOXICOPHOBIA n. the morbid fear of poisoning, also TOXIPHOBIA.
TOXOPLASMOSEStoxoplasmoses n. Plural of toxoplasmosis.
TOXOPLASMOSIS n. an infection of animals (esp. the domestic cat) and humans by microorganisms, prob protozoa, of the genus Toxoplasma.
TOXOPLASMOSIStoxoplasmosis n. A disease, caused by the parasite Toxoplasma gondii, that primarily affects felids, but also other mammals…
TOXOPLASMOSIS n. an infection of animals (esp. the domestic cat) and humans by microorganisms, prob protozoa, of the genus Toxoplasma.
XEROMORPHOUSxeromorphous adj. Xeromorphic.
XEROMORPHOUS adj. of parts of a plant, protected against excessive loss of water by thick cuticles, coatings of hairs and similar structural features, also XEROMORPHIC.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the 1Word.ws and WikWik.org.

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