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There are 8 fifteen-letter words containing O, 2S, 2T and X

AXIOMATISATIONSaxiomatisations n. Plural of axiomatisation.
AXIOMATISATION n. the act of reducing to a system of axioms, also AXIOMATIZATION.
CYTOTAXONOMISTScytotaxonomists n. Plural of cytotaxonomist.
CYTOTAXONOMIST n. a practitioner of cytotaxonomy.
EXCEPTIONALISTSexceptionalists n. Plural of exceptionalist.
EXCLAUSTRATIONSexclaustrations n. Plural of exclaustration.
EXCLAUSTRATION n. a release from religious vows to return to the secular world.
EXPLORATIONISTSexplorationists n. Plural of explorationist.
EXPLORATIONIST n. a scientist engaged in mineral exploration.
EXTENSIVISATIONEXTENSIVISATION n. the extensive method of agriculture, also EXTENSIVIZATION.
SINISTRODEXTRALsinistrodextral adj. Moving or directed from the left to the right.
SINISTRODEXTRAL adj. going or directed from left to right, as a sinistrodextral script.
XENOTRANSPLANTSxenotransplants n. Plural of xenotransplant.
XENOTRANSPLANT n. an operation in which an organ or tissue is transferred from one animal to another of a different species.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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