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There are 3 twelve-letter words containing 2O, P, 2T and Z

CRYPTOZOITEScryptozoites n. Plural of cryptozoite.
CRYPTOZOITE n. a malarial parasite at the stage of development in its host before it enters the red blood cells.
OPTIMIZATIONoptimization n. The design and operation of a system or process to make it as good as possible in some defined sense.
optimization n. (Programming) The reduction of a program or algorithm to its most efficient form, as during compilation…
OPTIMIZATION n. the act of optimizing, also OPTIMISATION.
TROPHOZOITEStrophozoites n. Plural of trophozoite.
TROPHOZOITE n. in Protozoa, the trophic phase of an adult.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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