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There are 7 eight-letter words containing 2O, R, T and X

BOXTHORNboxthorn n. Any plant of the genus Lycium.
BOXTHORN n. a thorny shrub with red berries.
FOXTROTSfoxtrots n. Plural of foxtrot.
foxtrots v. Third-person singular simple present indicative form of foxtrot.
FOXTROT v. to dance in a particular way with a partner.
NEXTDOORnextdoor adj. (Nonstandard) Alternative spelling of next-door.
nextdoor adv. (Nonstandard) Alternative spelling of next-door.
next-door adj. That occupies an adjacent place, especially the building immediately to the left or right.
ORTHODOXorthodox adj. Conforming to the accepted, established, or traditional doctrines of a given faith, religion, or ideology.
orthodox adj. Adhering to whatever is customary, traditional, or generally accepted.
orthodox adj. Of the eastern churches, Eastern Orthodox.
OXYTROPEoxytrope n. (Botany) Synonym of locoweed.
OXYTROPE n. a genus of plants in the legume family, including locoweed.
PROTOXIDprotoxid n. Archaic form of protoxide.
PROTOXID n. that one of a series of oxides having the lowest proportion of oxygen, also PROTOXIDE.
TOXOCARAToxocara prop.n. A taxonomic genus within the family Toxocaridae – certain parasitic nematodes that cause toxocariasis in humans.
TOXOCARA n. a kind of parasitic worm found in the intestines of dogs and cats.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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