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There are 16 ten-letter words containing N, 2O, P, S, T and U

ANATROPOUSanatropous adj. (Botany, of an ovule) Having an inverted nucleus, whose apex points to the base.
ANATROPOUS adj. of an ovule, inverted so that the micropyle is next to the stalk.
AUTOPOINTSAUTOPOINT n. a point-to-point over rough country in motor vehicles.
DOWNSPOUTSdownspouts n. Plural of downspout.
DOWNSPOUT n. (US) a drainpipe.
NONSUPPORTnonsupport n. (Uncountable)A lack of support.
nonsupport n. (Uncountable)The failure to provide for one’s family or other dependents.
nonsupport n. (Countable) One who fails to provide support.
OUTPASSIONoutpassion v. (Transitive, rare) To be more passionate than; to surpass in passion.
OUTPASSION v. to exceed in passion.
PHOTOTONUSphototonus n. Sensitivity to, or irritation caused by, light.
PHOTOTONUS n. the sensitivity of a living organism to light.
POLLUTIONSpollutions n. Plural of pollution.
POLLUTION n. making dirty, defilement.
PORTENTOUSportentous adj. Of momentous or ominous significance.
portentous adj. Ominously prophetic.
portentous adj. Puffed up with vanity.
POURPOINTSpourpoints n. Plural of pourpoint.
POURPOINT n. (French) a mediaeval quilted doublet.
PROTEINOUSproteinous adj. Proteinaceous.
PROTEINOUS adj. of or related to protein, also PROTEINACEOUS.
PROTRUSIONprotrusion n. (Uncountable) The act of protruding.
protrusion n. (Uncountable) The state of being protruded.
protrusion n. (Countable) Anything that protrudes.
PUFTALOONSpuftaloons n. Plural of puftaloon.
PUFTALOON n. (Australian) a type of fried cake, eaten hot with jam, honey or sugar, also PUFFTALOONAS, PUFTALOONIES.
SOUNDPOSTSsoundposts n. Plural of soundpost.
sound␣posts n. Plural of sound post.
SOUNDPOST n. a small post on guitars, violins etc. that joins the front surface to the back.
UNSTOOPINGunstooping adj. Not stooping.
UNSTOOPING adj. not stooping.
UPROOTINGSuprootings n. Plural of uprooting.
UPROOTING n. the act of uprooting.
UPSHOOTINGupshooting v. Present participle of upshoot.
UPSHOOT v. to shoot upwards.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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