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There are 14 ten-letter words containing N, 2O, P, S and 2T

AUTOPOINTSAUTOPOINT n. a point-to-point over rough country in motor vehicles.
ENTOPROCTSentoprocts n. Plural of entoproct.
ENTOPROCT n. any of a phylum of animals related to Bryozoans.
FOOTPRINTSfootprints n. Plural of footprint.
FOOTPRINT n. the mark left on the ground or floor by a person's or animal's foot.
MONOPTOTESmonoptotes n. Plural of monoptote.
MONOPTOTE n. a noun that has one grammatical case only.
NOSTOPATHYnostopathy n. A fear of returning home, for example after prison or military service.
NOSTOPATHY n. the morbid fear of returning to familiar places.
PHOTONASTYphotonasty n. A nastic response to a change in light levels.
PHOTONASTY n. the adoption of a certain position due to the effect of light on growth.
PHOTOTONUSphototonus n. Sensitivity to, or irritation caused by, light.
PHOTOTONUS n. the sensitivity of a living organism to light.
PHYTOTRONSphytotrons n. Plural of phytotron.
PHYTOTRON n. an apparatus that produces climates artificially for the study of plant growth.
PORTENTOUSportentous adj. Of momentous or ominous significance.
portentous adj. Ominously prophetic.
portentous adj. Puffed up with vanity.
PORTIONISTportionist n. One of the incumbents of a benefice that has two or more rectors or vicars.
portionist n. (Historical) A scholar at Merton College, Oxford, England, who has a certain academical allowance or portion.
PORTIONIST n. a postmaster of Merton College; one of two or more incumbents sharing a benefice.
PROTONATESprotonates v. Third-person singular simple present indicative form of protonate.
PROTONATE v. to acquire an additional proton.
STENOTOPICstenotopic adj. (Ecology) Able to tolerate or adapt to only a small range of environmental conditions.
STENOTOPIC adj. able to adapt only to a small range of environmental conditions, also STENOTROPIC.
TONOPLASTStonoplasts n. Plural of tonoplast.
TONOPLAST n. a semipermeable membrane surrounding a plant vacuole.
TOPONYMISTtoponymist n. One who studies toponymy.
TOPONYMIST n. one who studies toponymy, the study of place-names.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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