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There are 4 twelve-letter words containing 2N, 2O, P and Z

BENZOPHENONEbenzophenone n. (Organic chemistry, countable) Any of a class of aromatic ketones based on the parent compound diphenylketone…
benzophenone n. (Organic chemistry, uncountable) The compound diphenylmethanone.
BENZOPHENONE n. a colorless crystalline ketone used esp. as a perfume fixative and in sunscreens.
MONOPOLIZINGmonopolizing v. Present participle of monopolize.
MONOPOLIZE v. to get a monopoly of, also MONOPOLISE.
OPSONIZATIONopsonization n. (Immunology) The process or result of opsonizing.
OPSONIZATION n. the process of opsonizing, also OPSONISATION.
ZOOPLANKTONSzooplanktons n. Plural of zooplankton.
ZOOPLANKTON n. tiny, free-floating organisms in aquatic systems.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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