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There are 9 ten-letter words containing 2N, O, 2P and S

NONSUPPORTnonsupport n. (Uncountable)A lack of support.
nonsupport n. (Uncountable)The failure to provide for one’s family or other dependents.
nonsupport n. (Countable) One who fails to provide support.
OPPUGNANTSoppugnants n. Plural of oppugnant.
OPPUGNANT n. an opponent.
PEPSINOGENpepsinogen n. (Biochemistry) A zymogen that is converted into pepsin by the hydrochloric acid in the stomach.
PEPSINOGEN n. a substance in the mucous membrane of the stomach which converts into pepsin in a slightly acid medium.
POSTPONINGpostponing v. Present participle of postpone.
POSTPONE v. to put off to a future time.
PROPANONESPROPANONE n. a systematic name of acetone.
PROPENSIONpropension n. (Archaic) Propensity.
PROPENSION n. (Shakespeare) inclination, propensity.
PROPONENTSproponents n. Plural of proponent.
PROPONENT n. one who is making proposals.
UNOPPOSINGunopposing adj. Not offering opposition; unresisting.
UNOPPOSING adj. not opposing.
UNSTOPPINGunstopping v. Present participle of unstop.
UNSTOP v. to remove a stopper from.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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