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There are 14 eight-letter words containing N, P, 2R and U

PRESSRUNpressrun n. The number of copies of a publication printed at one time.
press␣run n. Alternative form of pressrun.
PRESSRUN n. a continuous operation of a printing press.
PRONEURSPRONEUR n. (French) a flatterer.
PROTURANproturan n. Any of many primitive insects, of the order Protura, that lack eyes and wings.
proturan adj. Of or pertaining to these insects.
PROTURAN n. any of an order of white wingless insects.
PRURIENTprurient adj. Uneasy with desire; itching; especially, having a lascivious anxiety or propensity; lustful.
prurient adj. Arousing or appealing to sexual desire.
prurient adj. Curious, especially inappropriately so.
PURPURINpurpurin n. A red anthraquinone dye, extracted from madder, that is used as a biological stain.
purpurin n. (Biochemistry) A protein of the lipocalin family.
purpurin n. (Historical) A brownish or deep red decorative glass used in ancient times.
PURRINGSpurrings n. Plural of purring.
PURRING n. the act of purring.
REPURINGrepuring v. Present participle of repure.
REPURE v. to purify again, also REPURIFY.
RESPRUNGresprung v. Simple past tense and past participle of respring.
RESPRING v. to replace the springs of.
RUNPROOFrunproof adj. (Of stockings) Not susceptible to runs.
RUNPROOF adj. (of stockings or tights) designed to be especially resistant to being ripped.
SPURNERSspurners n. Plural of spurner.
SPURNER n. one who spurns.
SPURRINGspurring v. Present participle of spur.
spurring n. An application of the spurs to a horse.
SPURRING n. the act of spurring.
SURPRINTsurprint n. The printing of text or graphics elements on top of a background that is a different tint of the same color.
surprint v. To print text or graphics elements on top of a background that is a different tint of the same color.
SURPRINT v. to print over printing.
UNPROPERunproper adj. (Obsolete) Improper, not according with fact or reason; wrong, irregular.
unproper adj. (Now rare) Improper, not suited for its use or application; inappropriate.
unproper adj. (Obsolete) Not belonging to a given person; someone else’s.
UNREPAIRunrepair n. An unsound state, as that of a building; dilapidation.
UNREPAIR n. a lack of repair.

Scrabble words — in black are valid world wide — in RED are not valid in North America — in GREEN are valid only in North America.
Definitions are short excerpt from the WikWik.org and 1Word.ws.

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